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Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing
Somatic mutation profiling in gastric cancer (GC) enables main driver mutations to be identified and their clinical and prognostic value to be evaluated. We investigated 77 tumour samples of GC by next-generation sequencing (NGS) with the Ion AmpliSeq Hotspot Panel v2 and a custom panel covering six...
Autores principales: | Nemtsova, Marina V., Kalinkin, Alexey I., Kuznetsova, Ekaterina B., Bure, Irina V., Alekseeva, Ekaterina A., Bykov, Igor I., Khorobrykh, Tatiana V., Mikhaylenko, Dmitry S., Tanas, Alexander S., Kutsev, Sergey I., Zaletaev, Dmitry V., Strelnikov, Vladimir V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965114/ https://www.ncbi.nlm.nih.gov/pubmed/31949278 http://dx.doi.org/10.1038/s41598-020-57544-3 |
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