Cargando…

DNase γ-dependent DNA fragmentation causes karyolysis in necrotic hepatocyte

Karyolysis is the complete dissolution of nuclear components of a dying cell. However, the generation mechanism has not been clarified. We studied a necrotic DNA fragmentation factor DNase γ (also known as DNase1L3) and previously found that karyolysis was inhibited in DNase γ deficient (DNase γ(−/−...

Descripción completa

Detalles Bibliográficos
Autores principales: TAKADA, Shuhei, WATANABE, Taiki, MIZUTA, Ryushin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983664/
https://www.ncbi.nlm.nih.gov/pubmed/31735730
http://dx.doi.org/10.1292/jvms.19-0499