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Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells

Goshajinkigan (GJG) is a traditional Japanese Kampo medicine used clinically to treat muscle pain in Japan. However, its underlying mechanism remains unclear. Since voltage-gated sodium channel (Nav) 1.4 is involved in skeletal muscle contraction, we investigated the possibility that GJG may affect...

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Detalles Bibliográficos
Autores principales: Imai, Ryota, Horita, Shoichiro, Ono, Yuko, Hagihara, Keisuke, Shimizu, Masaru, Maejima, Yuko, Shimomura, Kenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194311/
https://www.ncbi.nlm.nih.gov/pubmed/32368413
http://dx.doi.org/10.1089/biores.2019.0034