Evidence for GTKO/β4GalNT2KO Pigs as the Preferred Organ-source for Old World Nonhuman Primates as a Preclinical Model of Xenotransplantation

BACKGROUND. Triple-knockout (TKO) pigs (in which expression of the 3 known pig carbohydrate xenoantigens has been deleted) are likely to be an optimal source of organs for transplantation into human recipients, many of whom do not have natural antibodies against TKO pig cells. However, old world mon...

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Detalles Bibliográficos
Autores principales: Cui, Yehua, Yamamoto, Takayuki, Raza, Syed Sikandar, Morsi, Mahmoud, Nguyen, Huy Quoc, Ayares, David, Cooper, David K.C., Hara, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Xenotransplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382549/
https://www.ncbi.nlm.nih.gov/pubmed/32766438
http://dx.doi.org/10.1097/TXD.0000000000001038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382549/
https://www.ncbi.nlm.nih.gov/pubmed/32766438
http://dx.doi.org/10.1097/TXD.0000000000001038

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