Metformin attenuates cardiac remodeling in mice through the Nrf2/Keap1 signaling pathway

Obesity results in a variety of metabolic alterations that may contribute to abnormalities in cardiac structure and function. Although metformin (Met) has been previously reported to exhibit beneficial effects against cardiomyopathy associated obesity, the mechanism underlying this observation remai...

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Detalles Bibliográficos
Autores principales: Du, Jingxia, Zhu, Mengxi, Li, Hongchao, Liang, Gaofeng, Li, Yan, Feng, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388283/
https://www.ncbi.nlm.nih.gov/pubmed/32742327
http://dx.doi.org/10.3892/etm.2020.8764