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Urotensin II and urantide exert opposite effects on the cellular components of atherosclerotic plaque in hypercholesterolemic rabbits
Increasing levels of plasma urotensin II (UII) are positively associated with atherosclerosis. In this study we investigated the role of macrophage-secreted UII in atherosclerosis progression, and evaluated the therapeutic value of urantide, a potent competitive UII receptor antagonist, in atheroscl...
Autores principales: | Yu, Qing-qing, Cheng, Da-xin, Xu, Li-ran, Li, Yan-kui, Zheng, Xiao-ya, Liu, Yi, Li, Ya-feng, Liu, Hao-le, Bai, Liang, Wang, Rong, Fan, Jiang-lin, Liu, En-qi, Zhao, Si-hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468446/ https://www.ncbi.nlm.nih.gov/pubmed/31685976 http://dx.doi.org/10.1038/s41401-019-0315-8 |
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