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Ultrastructural and proapoptotic-like effects of kaempferol in Giardia duodenalis trophozoites and bioinformatics prediction of its potential protein target

BACKGROUND: Kaempferol (KPF) is a flavonoid with antiparasitic activity including experimental giardiasis which mechanism of action is unknown. OBJECTIVE: To analyse the cytotoxic effects of KPF on Giardia duodenalis trophozoites and to identify a likely parasite target of this compound. METHODS: We...

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Detalles Bibliográficos
Autores principales: Argüello-García, Raúl, Calzada, Fernando, García-Hernández, Normand, Chávez-Munguía, Bibiana, Velázquez-Domínguez, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577037/
https://www.ncbi.nlm.nih.gov/pubmed/33111756
http://dx.doi.org/10.1590/0074-02760200127