Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients

BACKGROUND: Recent studies indicated that exosomal programmed death-ligand 1 (PD-L1) derived from cancers could induce immunosuppression and tumor pathogenesis. However, it is unclear how exosomes influence osteosarcoma (OS) progression and whether PD-L1 also exists in serum exosomes (Sr-exosomes) o...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Zhang, Hongliang, Sun, Xin, Wang, Xiaofang, Ren, Tingting, Huang, Yi, Zhang, Ranxin, Zheng, Bingxin, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579953/
https://www.ncbi.nlm.nih.gov/pubmed/33092576
http://dx.doi.org/10.1186/s12951-020-00710-6