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Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Is a Negative Regulator of Oligodendrocyte Progenitor Cell Differentiation in the Adult Mouse Brain

Low-density lipoprotein receptor-related protein 1 (LRP1) is a large, endocytic cell surface receptor that is highly expressed by oligodendrocyte progenitor cells (OPCs) and LRP1 expression is rapidly downregulated as OPCs differentiate into oligodendrocytes (OLs). We report that the conditional del...

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Detalles Bibliográficos
Autores principales: Auderset, Loic, Pitman, Kimberley A., Cullen, Carlie L., Pepper, Renee E., Taylor, Bruce V., Foa, Lisa, Young, Kaylene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691426/
https://www.ncbi.nlm.nih.gov/pubmed/33282858
http://dx.doi.org/10.3389/fcell.2020.564351