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Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages

BACKGROUND: Liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs; liver resident macrophages) form the body’s most effective scavenger cell system for the removal of harmful blood-borne substances, ranging from modified self-proteins to pathogens and xenobiotics. Controversies in the li...

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Detalles Bibliográficos
Autores principales: Bhandari, Sabin, Li, Ruomei, Simón-Santamaría, Jaione, McCourt, Peter, Johansen, Steinar Daae, Smedsrød, Bård, Martinez-Zubiaurre, Inigo, Sørensen, Karen Kristine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694354/
https://www.ncbi.nlm.nih.gov/pubmed/33246411
http://dx.doi.org/10.1186/s12860-020-00331-9