Donor KIR3DL1/receptor HLA-Bw4-80I Combination Reduces Acute Leukemia Relapse after Umbilical Cord Blood Transplantation without in Vitro T-cell Depletion

BACKGROUND: Donor natural killer (NK) cell alloreactivity in umbilical cord bone marrow transplantation (UCBT) can lead to leukemic relapse. However, NK cell function is calibrated by interaction with human leukocyte antigens (HLAs). This study aimed to investigate graft-resistant leukemia after tra...

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Detalles Bibliográficos
Autores principales: Fang, Xinchen, Zhu, Xiaoyu, Tang, Baolin, Song, Kaidi, Yao, Wen, Wan, Xiang, Liu, Huilan, Peng, Jun, Sun, Zimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813285/
https://www.ncbi.nlm.nih.gov/pubmed/33489044
http://dx.doi.org/10.4084/MJHID.2021.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813285/
https://www.ncbi.nlm.nih.gov/pubmed/33489044
http://dx.doi.org/10.4084/MJHID.2021.005

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