Cardiomyocytes Derived from Induced Pluripotent Stem Cells as a Disease Model for Propionic Acidemia

Propionic acidemia (PA), one of the most frequent life-threatening organic acidemias, is caused by mutations in either the PCCA or PCCB genes encoding both subunits of the mitochondrial propionyl-CoA carboxylase (PCC) enzyme. Cardiac alterations (hypertrophy, dilated cardiomyopathy, long QT) are one...

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Detalles Bibliográficos
Autores principales: Alonso-Barroso, Esmeralda, Pérez, Belén, Desviat, Lourdes Ruiz, Richard, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865492/
https://www.ncbi.nlm.nih.gov/pubmed/33503868
http://dx.doi.org/10.3390/ijms22031161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865492/
https://www.ncbi.nlm.nih.gov/pubmed/33503868
http://dx.doi.org/10.3390/ijms22031161

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