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Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells
UDP-glucose-dehydrogenase (UGDH) synthesizes UDP-glucuronic acid. It is involved in epirubicin detoxification and hyaluronan synthesis. This work aimed to evaluate the effect of UGDH knockdown on epirubicin response and hyaluronan metabolism in MDA-MB-231 breast cancer cells. Additionally, the aim w...
Autores principales: | Vitale, Daiana L., Caon, Ilaria, Parnigoni, Arianna, Sevic, Ina, Spinelli, Fiorella M., Icardi, Antonella, Passi, Alberto, Vigetti, Davide, Alaniz, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914570/ https://www.ncbi.nlm.nih.gov/pubmed/33572239 http://dx.doi.org/10.3390/biom11020246 |
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