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Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins

Thioredoxins (Trxs) are ubiquitous enzymes that regulate the redox state in cells. In Drosophila, there are two germline-specific Trxs, Deadhead (Dhd) and thioredoxin T (TrxT), that belong to the lethal(3)malignant brain tumor signature genes and to the ‘survival network’ of genes that mediate the c...

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Detalles Bibliográficos
Autores principales: Freier, Regina, Aragón, Eric, Bagiński, Błażej, Pluta, Radoslaw, Martin-Malpartida, Pau, Ruiz, Lidia, Condeminas, Miriam, Gonzalez, Cayetano, Macias, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924233/
https://www.ncbi.nlm.nih.gov/pubmed/33708404
http://dx.doi.org/10.1107/S2052252521000221