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Insight into the direct interaction of Na(+) with NhaA and mechanistic implications
Na(+)/H(+) antiporters comprise a family of membrane proteins evolutionarily conserved in all kingdoms of life that are essential in cellular ion homeostasis. While several human homologues have long been drug targets, NhaA of Escherichia coli has become the paradigm for this class of secondary acti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007835/ https://www.ncbi.nlm.nih.gov/pubmed/33782459 http://dx.doi.org/10.1038/s41598-021-86318-8 |