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Insight into the direct interaction of Na(+) with NhaA and mechanistic implications

Na(+)/H(+) antiporters comprise a family of membrane proteins evolutionarily conserved in all kingdoms of life that are essential in cellular ion homeostasis. While several human homologues have long been drug targets, NhaA of Escherichia coli has become the paradigm for this class of secondary acti...

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Detalles Bibliográficos
Autores principales: Quick, Matthias, Dwivedi, Manish, Padan, Etana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007835/
https://www.ncbi.nlm.nih.gov/pubmed/33782459
http://dx.doi.org/10.1038/s41598-021-86318-8