Phosphatidylinositol Stabilizes Fluid-Phase Liposomes Loaded with a Melphalan Lipophilic Prodrug

Previously, a liposomal formulation of a chemotherapeutic agent melphalan (Mlph) incorporated in a fluid lipid bilayer of natural phospholipids in the form of dioleoylglyceride ester (MlphDG) was developed and the antitumor effect was confirmed in mouse models. The formulation composed of egg phosph...

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Detalles Bibliográficos
Autores principales: Tretiakova, Daria, Le-Deigen, Irina, Onishchenko, Natalia, Kuntsche, Judith, Kudryashova, Elena, Vodovozova, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067299/
https://www.ncbi.nlm.nih.gov/pubmed/33915726
http://dx.doi.org/10.3390/pharmaceutics13040473