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The Nesprin-1/-2 ortholog ANC-1 regulates organelle positioning in C. elegans independently from its KASH or actin-binding domains
KASH proteins in the outer nuclear membrane comprise the cytoplasmic half of linker of nucleoskeleton and cytoskeleton (LINC) complexes that connect nuclei to the cytoskeleton. Caenorhabditis elegans ANC-1, an ortholog of Nesprin-1/2, contains actin-binding and KASH domains at opposite ends of a lon...
Autores principales: | Hao, Hongyan, Kalra, Shilpi, Jameson, Laura E, Guerrero, Leslie A, Cain, Natalie E, Bolivar, Jessica, Starr, Daniel A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139857/ https://www.ncbi.nlm.nih.gov/pubmed/33860766 http://dx.doi.org/10.7554/eLife.61069 |
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