X-ROS Signaling Depends on Length-Dependent Calcium Buffering by Troponin

The stretching of a cardiomyocyte leads to the increased production of reactive oxygen species that increases ryanodine receptor open probability through a process termed X-ROS signaling. The stretching of the myocyte also increases the calcium affinity of myofilament Troponin C, which increases its...

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Detalles Bibliográficos
Autores principales: Limbu, Sarita, Prosser, Benjamin L., Lederer, William J., Ward, Christopher W., Jafri, Mohsin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152234/
https://www.ncbi.nlm.nih.gov/pubmed/34068012
http://dx.doi.org/10.3390/cells10051189