X-ROS Signaling Depends on Length-Dependent Calcium Buffering by Troponin
The stretching of a cardiomyocyte leads to the increased production of reactive oxygen species that increases ryanodine receptor open probability through a process termed X-ROS signaling. The stretching of the myocyte also increases the calcium affinity of myofilament Troponin C, which increases its...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152234/ https://www.ncbi.nlm.nih.gov/pubmed/34068012 http://dx.doi.org/10.3390/cells10051189 |