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A controlled T7 transcription-driven symmetric amplification cascade machinery for single-molecule detection of multiple repair glycosylases

Genomic oxidation and alkylation are two of the most important forms of cytotoxic damage that may induce mutagenesis, carcinogenicity, and teratogenicity. Human 8-oxoguanine (hOGG1) and alkyladenine DNA glycosylases (hAAG) are responsible for two major forms of oxidative and alkylative damage repair...

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Detalles Bibliográficos
Autores principales: Wang, Li-juan, Liang, Le, Liu, Bing-jie, Jiang, BingHua, Zhang, Chun-yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179622/
https://www.ncbi.nlm.nih.gov/pubmed/34168791
http://dx.doi.org/10.1039/d1sc00189b