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Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations
Metabolic adaptations to complex perturbations, like the response to pharmacological treatments in multifactorial diseases such as cancer, can be described through measurements of part of the fluxes and concentrations at the systemic level and individual transporter and enzyme activities at the mole...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336858/ https://www.ncbi.nlm.nih.gov/pubmed/34297714 http://dx.doi.org/10.1371/journal.pcbi.1009234 |