Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations

Metabolic adaptations to complex perturbations, like the response to pharmacological treatments in multifactorial diseases such as cancer, can be described through measurements of part of the fluxes and concentrations at the systemic level and individual transporter and enzyme activities at the mole...

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Detalles Bibliográficos
Autores principales: de Atauri, Pedro, Tarrado-Castellarnau, Míriam, Tarragó-Celada, Josep, Foguet, Carles, Karakitsou, Effrosyni, Centelles, Josep Joan, Cascante, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336858/
https://www.ncbi.nlm.nih.gov/pubmed/34297714
http://dx.doi.org/10.1371/journal.pcbi.1009234