Effect of the Non-Immunosuppressive MPT Pore Inhibitor Alisporivir on the Functioning of Heart Mitochondria in Dystrophin-Deficient mdx Mice

Supporting mitochondrial function is one of the therapeutic strategies that improve the functioning of skeletal muscle in Duchenne muscular dystrophy (DMD). In this work, we studied the effect of a non-immunosuppressive inhibitor of mitochondrial permeability transition pore (MPTP) alisporivir (5 mg...

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Detalles Bibliográficos
Autores principales: Dubinin, Mikhail V., Starinets, Vlada S., Talanov, Eugeny Yu., Mikheeva, Irina B., Belosludtseva, Natalia V., Serov, Dmitriy A., Tenkov, Kirill S., Belosludtseva, Evgeniya V., Belosludtsev, Konstantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466941/
https://www.ncbi.nlm.nih.gov/pubmed/34572419
http://dx.doi.org/10.3390/biomedicines9091232