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Defining the fetal origin of MLL-AF4 infant leukemia highlights specific fatty acid requirements
Infant MLL-AF4-driven acute lymphoblastic leukemia (ALL) is a devastating disease with dismal prognosis. A lack of understanding of the unique biology of this disease, particularly its prenatal origin, has hindered improvement of survival. We perform multiple RNA sequencing experiments on fetal, neo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567312/ https://www.ncbi.nlm.nih.gov/pubmed/34706236 http://dx.doi.org/10.1016/j.celrep.2021.109900 |