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Order through destruction: how ER‐associated protein degradation contributes to organelle homeostasis

The endoplasmic reticulum (ER) is a large, dynamic, and multifunctional organelle. ER protein homeostasis is essential for the coordination of its diverse functions and depends on ER‐associated protein degradation (ERAD). The latter process selects target proteins in the lumen and membrane of the ER...

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Detalles Bibliográficos
Autores principales: Christianson, John C, Carvalho, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922271/
https://www.ncbi.nlm.nih.gov/pubmed/35170763
http://dx.doi.org/10.15252/embj.2021109845