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ATP synthase inhibitory factor subunit 1 regulates islet β-cell function via repression of mitochondrial homeostasis

Mitochondrial homeostasis is crucial for the function of pancreatic β-cells. ATP synthase inhibitory factor subunit 1 (IF1) is a mitochondrial protein interacting with ATP synthase to inhibit its enzyme activity. IF1 may also play a role in maintaining ATP synthase oligomerization and mitochondrial...

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Detalles Bibliográficos
Autores principales: Zhang, Kailiang, Bao, Rong, Huang, Fengyuan, Yang, Kevin, Ding, Yishu, Lauterboeck, Lothar, Yoshida, Masasuke, Long, Qinqiang, Yang, Qinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198815/
https://www.ncbi.nlm.nih.gov/pubmed/34608240
http://dx.doi.org/10.1038/s41374-021-00670-x