Unbalanced Regulation of Sec22b and Ykt6 Blocks Autophagosome Axonal Retrograde Flux in Neuronal Ischemia–Reperfusion Injury

Cerebral ischemia–reperfusion (I/R) injury in ischemic penumbra is accountable for poor outcome of ischemic stroke patients receiving recanalization therapy. Compelling evidence previously demonstrated a dual role of autophagy in stroke. This study aimed to understand the traits of autophagy in the...

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Detalles Bibliográficos
Autores principales: Li, Haiying, Li, Xiang, Xu, Zhongmou, Lu, Jinxin, Cao, Chang, You, Wanchun, Yu, Zhengquan, Shen, Haitao, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295843/
https://www.ncbi.nlm.nih.gov/pubmed/35654605
http://dx.doi.org/10.1523/JNEUROSCI.2030-21.2022