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Protocol to quantify and phenotype SARS-CoV-2-specific T cell response using a rapid flow-cytometry-based whole blood assay

Monitoring antigen-specific T cell frequency, function, and phenotype is essential to assess the host immune response to pathogens or novel vaccines. Here, we describe a rapid and simple ex vivo whole blood assay to detect and phenotype the SARS-CoV-2-specific T cell response. We detail steps for wh...

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Detalles Bibliográficos
Autores principales: Mutavhatsindi, Hygon, Riou, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510067/
https://www.ncbi.nlm.nih.gov/pubmed/36272131
http://dx.doi.org/10.1016/j.xpro.2022.101771