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Depletion and Reversal of Hepatocellular Carcinoma Inducing CTL through ER Stress-Dependent PERK-CHOP Signaling Pathway

AIMS: In this report, it was investigated that hepatoma cells can cause downregulation of cytotoxic T lymphocyte (CTL) function and tea polyphenols (TPs) can reverse downregulation of CTL function. METHODS: The expression of GRP78, PD-1, and TIM-3 was detected by western blotting in CTLL-2 coculture...

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Detalles Bibliográficos
Autores principales: Guo, Mengnan, Wang, Wei, Bai, Wen, Bai, Zekun, Chen, Weixi, Su, Yali, Wu, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576428/
https://www.ncbi.nlm.nih.gov/pubmed/36262827
http://dx.doi.org/10.1155/2022/6413783