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Apalutamide and autophagy inhibition in a xenograft mouse model of human prostate cancer
BACKGROUND: Apalutamide (APA) is a next-generation androgen receptor antagonist for the treatment of advanced prostate cancer. We have previously shown that upregulation of autophagy is one of the mechanisms by which prostate cancer (PC) cells survive APA anti-tumor treatment in vitro. Therefore, we...
Autores principales: | Eberli, Daniel, Kranzbühler, Benedikt, Prause, Lukas, Baumgartner, Valentin, Preda, Sheryl, Sousa, Rosa, Lehner, Fabienne, Salemi, Souzan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587065/ https://www.ncbi.nlm.nih.gov/pubmed/35751683 http://dx.doi.org/10.1007/s00432-022-04059-1 |
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