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Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients

OBJECTIVE: A comprehensive immune landscape for HBV infection is pivotal to achieve HBV cure. DESIGN: We performed single-cell RNA sequencing of 2 43 000 cells from 46 paired liver and blood samples of 23 individuals, including six immune tolerant, 5 immune active (IA), 3 acute recovery (AR), 3 chro...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Li, Jiesheng, Cheng, Yongqian, Meng, Fanping, Song, Jin-Wen, Fan, Xing, Fan, Hongtao, Li, Jing, Fu, Yu-Long, Zhou, Ming-Ju, Hu, Wei, Wang, Si-Yu, Fu, Yuan-Jie, Zhang, Ji-Yuan, Xu, Ruo-Nan, Shi, Ming, Hu, Xueda, Zhang, Zemin, Ren, Xianwen, Wang, Fu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763233/
https://www.ncbi.nlm.nih.gov/pubmed/35361683
http://dx.doi.org/10.1136/gutjnl-2021-325915