Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure
Nicotinamide adenine dinucleotide (NAD(+)) is an essential cofactor of critical enzymes including protein deacetylase sirtuins/SIRTs and its levels in mammalian cells rely on the nicotinamide phosphoribosyltransferase (NAMPT)-mediated salvage pathway. Intracellular NAMPT (iNAMPT) is secreted and fou...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082796/ https://www.ncbi.nlm.nih.gov/pubmed/37031230 http://dx.doi.org/10.1038/s41467-023-37517-6 |