Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

The DNA sensor cyclic GMP-AMP synthase (cGAS) is critical in host antiviral immunity. Vaccinia virus (VACV) is a large cytoplasmic DNA virus that belongs to the poxvirus family. How vaccinia virus antagonizes the cGAS-mediated cytosolic DNA-sensing pathway is not well understood. In this study, we s...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Wang, Yi, Dai, Peihong, Li, Tuo, Zierhut, Christian, Tan, Adrian, Zhang, Tuo, Xiang, Jenny Zhaoying, Ordureau, Alban, Funabiki, Hironori, Chen, Zhijian, Deng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201048/
https://www.ncbi.nlm.nih.gov/pubmed/37217469
http://dx.doi.org/10.1038/s41467-023-38514-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201048/
https://www.ncbi.nlm.nih.gov/pubmed/37217469
http://dx.doi.org/10.1038/s41467-023-38514-5

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