Cargando…
A newly-synthesized compound CP-07 alleviates microglia-mediated neuroinflammation and ischemic brain injury via inhibiting STAT3 phosphorylation
BACKGROUND AND OBJECTIVES: Overactivated glial cells, especially microglia, are core components in the progression of pathologic neuroinflammation, and the application of anti-inflammatory reagents has been regarded as a potential therapy in the management of infarction/reperfusion (I/R) brain injur...
Autores principales: | Guo, Mengdi, Cao, Qian, Xia, Shengnan, Cao, Xiang, Chen, Jian, Qian, Yi, Bao, Xinyu, Xu, Yun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318917/ https://www.ncbi.nlm.nih.gov/pubmed/37408577 http://dx.doi.org/10.2478/jtim-2023-0090 |
Ejemplares similares
-
A monoamine oxidase B inhibitor ethyl ferulate suppresses microglia-mediated neuroinflammation and alleviates ischemic brain injury
por: Zou, Xinxin, et al.
Publicado: (2022) -
Fraxetin alleviates microglia-mediated neuroinflammation after ischemic stroke
por: Deng, Shi-Ji, et al.
Publicado: (2022) -
Regulation of Microglia-Activation-Mediated Neuroinflammation to Ameliorate Ischemia-Reperfusion Injury via the STAT5-NF-κB Pathway in Ischemic Stroke
por: Pu, Zhijun, et al.
Publicado: (2022) -
Pharmacological Upregulation of Microglial Lipid Droplet Alleviates Neuroinflammation and Acute Ischemic Brain Injury
por: Li, Huiya, et al.
Publicado: (2023) -
Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke
por: Chen, Shuang, et al.
Publicado: (2017)