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Enantioselective 1,3-Dipolar Cycloadditions of α-Methylene Lactams to Construct Spirocycles

[Image: see text] Spirocyclic scaffolds are important motifs due to their potential to bestow favorable effects on pharmaceutical compounds. However, there is a need for efficient methods for their enantioselective construction. We report a method for the asymmetric 1,3-dipolar cycloaddition of diaz...

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Detalles Bibliográficos
Autores principales: Nishiura, Yuji, Gonzalez, Kevin J., Cusumano, Alexander Q., Stoltz, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496134/
https://www.ncbi.nlm.nih.gov/pubmed/37643480
http://dx.doi.org/10.1021/acs.orglett.3c01978