Lipid Nanoparticle-Mediated Hit-and-Run Approaches Yield Efficient and Safe In Situ Gene Editing in Human Skin

[Image: see text] Despite exciting advances in gene editing, the efficient delivery of genetic tools to extrahepatic tissues remains challenging. This holds particularly true for the skin, which poses a highly restrictive delivery barrier. In this study, we ran a head-to-head comparison between Cas9...

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Detalles Bibliográficos
Autores principales: Bolsoni, Juliana, Liu, Danny, Mohabatpour, Fatemeh, Ebner, Ronja, Sadhnani, Gaurav, Tafech, Belal, Leung, Jerry, Shanta, Selina, An, Kevin, Morin, Tessa, Chen, Yihang, Arguello, Alfonso, Choate, Keith, Jan, Eric, Ross, Colin J.D., Brambilla, Davide, Witzigmann, Dominik, Kulkarni, Jayesh, Cullis, Pieter R., Hedtrich, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655174/
https://www.ncbi.nlm.nih.gov/pubmed/37918441
http://dx.doi.org/10.1021/acsnano.3c08644

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