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Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice.
We examined a database of 379 long-term carcinogenicity studies in rats and mice to evaluate sex and species correlations in site-specific carcinogenic responses. Within a species, most target sites showed a strong correlation between males and females. For example, chemicals producing forestomach o...
Autores principales: | Haseman, J K, Lockhart, A M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519653/ https://www.ncbi.nlm.nih.gov/pubmed/8513764 |
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