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Complement 1 Inhibitor Is a Regulator of the Alternative Complement Pathway
We studied complement 1 inhibitor (C1-INH) as an inhibitor of the alternative complement pathway. C1-INH prevented lysis, induced by the alternative complement pathway, of paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes in human serum. It inhibited the binding of both factors B and C3 to PNH...
Autores principales: | Jiang, Haixiang, Wagner, Eric, Zhang, Huamei, Frank, Michael M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193533/ https://www.ncbi.nlm.nih.gov/pubmed/11733575 |
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