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Regulation of CCL2 Expression by an Upstream TALE Homeodomain Protein-Binding Site That Synergizes with the Site Created by the A-2578G SNP

CC Chemokine Ligand 2 (CCL2) is a potent chemoattractant produced by macrophages and activated astrocytes during periods of inflammation within the central nervous system. Increased CCL2 expression is correlated with disease progression and severity, as observed in pulmonary tuberculosis, HCV-relate...

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Detalles Bibliográficos
Autores principales: Page, Stephen H., Wright, Edward K., Gama, Lucio, Clements, Janice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132772/
https://www.ncbi.nlm.nih.gov/pubmed/21760952
http://dx.doi.org/10.1371/journal.pone.0022052