Cargando…
Statistical Considerations of Optimal Study Design for Human Plasma Proteomics and Biomarker Discovery
[Image: see text] A mass spectrometry-based plasma biomarker discovery workflow was developed to facilitate biomarker discovery. Plasma from either healthy volunteers or patients with pancreatic cancer was 8-plex iTRAQ labeled, fractionated by 2-dimensional reversed phase chromatography and subjecte...
Autores principales: | Zhou, Cong, Simpson, Kathryn L., Lancashire, Lee J., Walker, Michael J., Dawson, Martin J., Unwin, Richard D., Rembielak, Agata, Price, Patricia, West, Catharine, Dive, Caroline, Whetton, Anthony D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320746/ https://www.ncbi.nlm.nih.gov/pubmed/22338609 http://dx.doi.org/10.1021/pr200636x |
Ejemplares similares
-
Quantitative mass spectrometry-based techniques for clinical use: Biomarker identification and quantification()
por: Simpson, Kathryn L., et al.
Publicado: (2009) -
Proteomic Workflows for Biomarker Identification Using Mass Spectrometry — Technical and Statistical Considerations during Initial Discovery
por: Orton, Dennis J., et al.
Publicado: (2013) -
Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value
por: Walker, Michael J., et al.
Publicado: (2015) -
Integrated Chemometrics and Statistics to Drive Successful Proteomics Biomarker Discovery
por: Suppers, Anouk, et al.
Publicado: (2018) -
Complex and prolonged skin toxicity after superficial brachytherapy for basal cell carcinoma on the lower leg
por: Rembielak, Agata
Publicado: (2020)