Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319

Fibroblast growth factor 21 is a novel hormonal regulator with the potential to treat a broad variety of metabolic abnormalities, such as type 2 diabetes, obesity, hepatic steatosis, and cardiovascular disease. Human recombinant wild type FGF21 (FGF21) has been shown to ameliorate metabolic disorder...

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Detalles Bibliográficos
Autores principales: Kharitonenkov, Alexei, Beals, John M., Micanovic, Radmila, Strifler, Beth A., Rathnachalam, Radhakrishnan, Wroblewski, Victor J., Li, Shun, Koester, Anja, Ford, Amy M., Coskun, Tamer, Dunbar, James D., Cheng, Christine C., Frye, Christopher C., Bumol, Thomas F., Moller, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594191/
https://www.ncbi.nlm.nih.gov/pubmed/23536797
http://dx.doi.org/10.1371/journal.pone.0058575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594191/
https://www.ncbi.nlm.nih.gov/pubmed/23536797
http://dx.doi.org/10.1371/journal.pone.0058575

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