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Surfactant Protein-A Modulates LPS-Induced TLR4 Localization and Signaling via β-Arrestin 2
The soluble C-type lectin surfactant protein (SP)-A mediates lung immune responses partially via its direct effects on alveolar macrophages (AM), the main resident leukocytes exposed to antigens. SP-A modulates the AM threshold of lipopolysaccharide (LPS) activity towards an anti-inflammatory phenot...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607558/ https://www.ncbi.nlm.nih.gov/pubmed/23536892 http://dx.doi.org/10.1371/journal.pone.0059896 |