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Surfactant Protein-A Modulates LPS-Induced TLR4 Localization and Signaling via β-Arrestin 2

The soluble C-type lectin surfactant protein (SP)-A mediates lung immune responses partially via its direct effects on alveolar macrophages (AM), the main resident leukocytes exposed to antigens. SP-A modulates the AM threshold of lipopolysaccharide (LPS) activity towards an anti-inflammatory phenot...

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Detalles Bibliográficos
Autores principales: Sender, Vicky, Lang, Linda, Stamme, Cordula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607558/
https://www.ncbi.nlm.nih.gov/pubmed/23536892
http://dx.doi.org/10.1371/journal.pone.0059896