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The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs

The Split Ends (SPEN) protein was originally discovered in Drosophila in the late 1990s. Since then, homologous proteins have been identified in eukaryotic species ranging from plants to humans. Every family member contains three predicted RNA recognition motifs (RRMs) in the N-terminal region of th...

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Detalles Bibliográficos
Autores principales: Arieti, Fabiana, Gabus, Caroline, Tambalo, Margherita, Huet, Tiphaine, Round, Adam, Thore, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041450/
https://www.ncbi.nlm.nih.gov/pubmed/24748666
http://dx.doi.org/10.1093/nar/gku277