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Periostin Expression is Altered in Aortic Valves in Smad6 Mutant Mice
Smad6 is known to predominantly inhibit BMP signaling by negatively regulating the BMP signaling process. Therefore, Smad6 mutation potentially provides an important genetic model for investigating the role of BMP signaling in vivo. Periostin is a 90-kDA secreted extracellular matrix (ECM) protein a...
Autores principales: | Sugi, Yukiko, Kern, Michael J, Markwald, Roger R, Burnside, Jessica L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224111/ https://www.ncbi.nlm.nih.gov/pubmed/25383261 http://dx.doi.org/10.4172/2167-0897.1000101 |
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