Periostin Expression is Altered in Aortic Valves in Smad6 Mutant Mice

Smad6 is known to predominantly inhibit BMP signaling by negatively regulating the BMP signaling process. Therefore, Smad6 mutation potentially provides an important genetic model for investigating the role of BMP signaling in vivo. Periostin is a 90-kDA secreted extracellular matrix (ECM) protein a...

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Detalles Bibliográficos
Autores principales: Sugi, Yukiko, Kern, Michael J, Markwald, Roger R, Burnside, Jessica L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224111/
https://www.ncbi.nlm.nih.gov/pubmed/25383261
http://dx.doi.org/10.4172/2167-0897.1000101

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