5-Hydroxytryptamine (5-HT) Cellular Sequestration during Chronic Exposure Delays 5-HT(3) Receptor Resensitization due to Its Subsequent Release

The serotonergic synapse is dynamically regulated by serotonin (5-hydroxytryptamine (5-HT)) with elevated levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, including the 5-HT type-3 (5-HT(3)) receptors. We report that recombinantly expressed 5-HT(3)...

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Detalles Bibliográficos
Autores principales: Hothersall, J. Daniel, Alexander, Amy, Samson, Andrew J., Moffat, Christopher, Bollan, Karen A., Connolly, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Membrane Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231679/
https://www.ncbi.nlm.nih.gov/pubmed/25281748
http://dx.doi.org/10.1074/jbc.M114.594796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231679/
https://www.ncbi.nlm.nih.gov/pubmed/25281748
http://dx.doi.org/10.1074/jbc.M114.594796

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