The histone deacetylase Hdac1 regulates inflammatory signalling in intestinal epithelial cells

BACKGROUND: It has recently been found that both nuclear epithelial-expressed histone deacetylases Hdac1 and Hdac2 are important to insure intestinal homeostasis and control the mucosal inflammatory response in vivo. In addition, HDAC inhibitors modulate epithelial cell inflammatory responses in can...

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Detalles Bibliográficos
Autores principales: Gonneaud, Alexis, Gagné, Julie Moore, Turgeon, Naomie, Asselin, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299484/
https://www.ncbi.nlm.nih.gov/pubmed/25606026
http://dx.doi.org/10.1186/s12950-014-0043-2