Systematic reconstruction of binding and stability landscapes of the fluorogenic aptamer spinach

Fluorogenic RNAs that are based on the complex formed by 3,5-difluoro-4-hydroxybenzylidene imidazolinone (DFHBI) derivatives and the RNA aptamer named Spinach were used to engineer a new generation of in vitro and in vivo sensors for bioanalytics. With the resolved crystal structure of the RNA/small...

Descripción completa

Detalles Bibliográficos
Autores principales: Ketterer, Simon, Fuchs, David, Weber, Wilfried, Meier, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627091/
https://www.ncbi.nlm.nih.gov/pubmed/26400180
http://dx.doi.org/10.1093/nar/gkv944