Tregs Modulate Lymphocyte Proliferation, Activation, and Resident-Memory T-Cell Accumulation within the Brain during MCMV Infection

Accumulation and retention of regulatory T-cells (Tregs) has been reported within post viral-encephalitic brains, however, the full extent to which these cells modulate neuroinflammation is yet to be elucidated. Here, we used Foxp3-DTR (diphtheria toxin receptor) knock-in transgenic mice, which upon...

Descripción completa

Detalles Bibliográficos
Autores principales: Prasad, Sujata, Hu, Shuxian, Sheng, Wen S., Singh, Amar, Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697843/
https://www.ncbi.nlm.nih.gov/pubmed/26720146
http://dx.doi.org/10.1371/journal.pone.0145457