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Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies

PURPOSE: In pharmacogenetic research, genetic variation in non-responders and high responders is compared with the aim to identify the genetic loci responsible for this variation in response. However, an important question is whether the non-responders are truly biologically non-responsive or actual...

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Detalles Bibliográficos
Autores principales:	Trompet, S., Postmus, I., Slagboom, P. E., Heijmans, B. T., Smit, R. A. J., Maier, A. B., Buckley, B. M., Sattar, N., Stott, D. J., Ford, I., Westendorp, R. G. J., de Craen, A. J. M., Jukema, J. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Pharmacogenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792342/ https://www.ncbi.nlm.nih.gov/pubmed/26686871 http://dx.doi.org/10.1007/s00228-015-1994-9

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