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Low-Level Stress Induces Production of Neuroprotective Factors in Wild-Type but Not BDNF(+/-) Mice: Interleukin-10 and Kynurenic Acid
BACKGROUND: Brain-derived neurotrophic factor (BDNF) deficiency confers vulnerability to stress, but the mechanisms are unclear. BDNF(+/-) mice exhibit behavioral, physiological, and neurochemical changes following low-level stress that are hallmarks of major depression. After immune challenge, neur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815464/ https://www.ncbi.nlm.nih.gov/pubmed/26232788 http://dx.doi.org/10.1093/ijnp/pyv089 |