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Population pharmacokinetic modeling of glibenclamide in poorly controlled South African type 2 diabetic subjects
AIM: The aim of this study was to describe the pharmacokinetics (PK) of glibenclamide in poorly controlled South African type 2 diabetic subjects using noncompartmental and model-based methods. METHODS: A total of 24 subjects with type 2 diabetes were administered increasing doses (0 mg/d, 2.5 mg/d,...
Autores principales: | Rambiritch, Virendra, Naidoo, Poobalan, Maharaj, Breminand, Pillai, Goonaseelan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948726/ https://www.ncbi.nlm.nih.gov/pubmed/27471411 http://dx.doi.org/10.2147/CPAA.S102676 |
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