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Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery
Intranasal administration provides a non-invasive drug delivery route that has been proposed to target macromolecules either to the brain via direct extracellular cranial nerve-associated pathways or to the periphery via absorption into the systemic circulation. Delivering drugs to nasal regions tha...
Autores principales: | Kumar, Niyanta N., Gautam, Mohan, Lochhead, Jeffrey J., Wolak, Daniel J., Ithapu, Vamsi, Singh, Vikas, Thorne, Robert G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997340/ https://www.ncbi.nlm.nih.gov/pubmed/27558973 http://dx.doi.org/10.1038/srep31732 |
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